News

Article

26 April 2023

Redaction: JT

IVPC/CIRI Virtual Seminar - Laurent Chatel-Chaix

Erratum. Please note the date change: The seminar will be held on Thursday 29th, September (and not 22 as previously announced) 2022. Dr Laurent Chatel-Chaix – Professeur agrégé – Institut national de la recherche scientifique, Centre Armand-Frappier Santé Biotechnologie (Laval, Québec, Canada) «Mitochondrial manipulations by flaviviruses »
Article

26 April 2023

Redaction: JT

Seminar from Pr Yorifumi Satou

Invited seminar from Pr Yorifumi Satou – Kumamoto University (Japan) – on Monday 12th of September 2022 entitled «Single-cell analysis to elucidate mechanisms underlying oncogenesis caused by HTLV-1»
Article

26 April 2023

Redaction: FA

Delphine Destoumieux-Garzon conference as part of the InfectioTron scientific animation

Human and environmental influence on the emergence of pathogens in the marine environment
Article

29 June 2023

Redaction: Clx

IVPC Virtual Seminar – Anat Melamed

Dr Anat Melamed - Imperial College London, UK- IVPC VIRUTAL seminar - Thursday 24th of March 2022, 1pm on Zoom – “Selective clonal persistence of HTLV-1 in vivo: radial chromatin organization, integration site and host transcription
Article

26 April 2023

Redaction: FA

Wednesday 26 January 2022 - EquipEx+ InfectioTron launch conference

The EquipEx InfectioTron, of which IVPC is a partner and co-leader, aims to develop the Lyon ecosystem to implement the "One Health" concept in the field of emerging infectious diseases.
Article

26 April 2023

Redaction: clx

Three new PhD students

Yu Gu, Maëva Duboeuf and Benjamin Riocreux-Verney : Three new PhD students in our teams
Article

26 April 2023

Redaction: Clx

Vincent Raquin is a new associate professor EPHE within the BUNYA team

New researcher in vector biology in the BUNYA team
Article

26 April 2023

Redaction: PYL

Identification of two pathways for SARS-CoV-2 entry into cells

A joint investigation by IVPC and University Heidelberg has revealed the mechanisms by which SARS-CoV-2 enters host cells
Article

26 April 2023

Redaction: MR

EPHE assistant professor position EPHE (n° 3231 « « Transmission of arboviruses by their arthropod vectors »)

An EPHE assistant professor position EPHE (n° 3231 « « Transmission of arboviruses by their arthropod vectors ») is now opened in the "Biology of bunyavirales" group
Article

26 April 2023

Redaction: FA

InfectioTron project, Laureate of the EQUIPEX national call

Network of contained platforms for the integrative and multidisciplinary study of infectious diseases
Article

26 April 2023

Redaction: MP

Congratulations to Marie-Pierre Confort, newly graduated from the "Ecole Pratique des Hautes Etudes" (Diplôme SVT de l’EPHE)!

« Rôle des protéines IFITMs (Interferon Induced Transmembrane proteins) dans la réponse antivirale innée contre le virus de la Fièvre de la Vallée du Rift (RVFV) ».
Article

26 April 2023

Redaction: LC

Congratulations to Dr Lucie Cappuccio!

Lucie Cappuccio ("Alphavirus transmission and comparative pathology" team) has defended her PhD on December, 15th, 2020 on her work entitled "Role of p53 during chikungunya virus infection, in mammal and insect"
Article

29 June 2023

Redaction: CM

Infection of Mammals and Mosquitoes by Alphaviruses: Involvement of Cell Death

Alphaviruses, such as the chikungunya virus, are emerging and re-emerging viruses that pose a global public health threat. They are transmitted by blood-feeding arthropods, mainly mosquitoes, to humans and animals. Although alphaviruses cause debilitating diseases in mammalian hosts, it appears that they have no pathological effect on the mosquito vector. Alphavirus/host interactions are increasingly studied at cellular and molecular levels. While it seems clear that apoptosis plays a key role in some human pathologies, the role of cell death in determining the outcome of infections in mosquitoes remains to be fully understood. Here, we review the current knowledge on alphavirus-induced regulated cell death in hosts and vectors and the possible role they play in determining tolerance or resistance of mosquitoes.
Article

29 June 2023

Redaction: VC

In vivo demonstration of pulmonary microvascular involvement in COVID-19 using Dual-Energy Computed Tomography

Prof. Vincent Cottin, and Prof. Jean-François Mornex, participated in a study on damage to the micro-vessels of the lung during infection with SARS-COV-2 using a dual energy spectral scanner allowing the specific analysis of pulmonary perfusion
Article

26 April 2023

Redaction: MR

Short piece on mosquito vector-borne diseases

A short piece on mosquito vector-borne diseases was published in L’Éphéméride, the EPHE
Article

26 April 2023

Redaction: Lozach PY

A viral protein exhibits biochemical properties similar to those of prions

Researchers from IVPC have recently discovered that a virus affecting ruminants in Africa can form amyloid-like fibrils in the brain
Article

26 April 2023

Redaction: MR

Viral infection impacts transposable element transcript amounts in Drosophila

Transposable elements (TEs) are genomic parasites that are found in all genomes, some of which display sequence similarity to certain viruses. In insects, TEs are controlled by the Piwi-interacting small interfering RNA (piRNA) pathway in gonads, while the small interfering RNA (siRNA) pathway is dedicated to TE somatic control and defense against viruses. So far, these two small interfering RNA pathways are considered to involve distinct molecular effectors and are described as independent. Using Sindbis virus (SINV) in Drosophila, here we show that viral infections affect TE transcript amounts via modulations of the piRNA and siRNA repertoires, with the clearest effects in somatic tissues. These results suggest that viral acute or chronic infections may impact TE activity and, thus, the tempo of genetic diversification. In addition, these results deserve further evolutionary considerations regarding potential benefits to the host, the virus, or the TEs.
Article

26 April 2023

Redaction: FA

In tribute to Pr Pierre Boulanger

Pr Pierre Boulanger, virologist and emeritus professor of the Lyon 1 university, died in Lyon on March 30th 2020
Article

26 April 2023

Redaction: VC

The CORTI-COVID trial

Therapeutic trial of oral corticosteroids in viral pneumonitis induced by SARS-Cov-2
Article

26 April 2023

Redaction: CL

Jocelyn Turpin joined IVPC

Jocelyn Turpin, previously at the Imperial College London, started, as INRAE research scientist, at IVPC on May 1st, 2020.